Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503435 | 1.00 | KMT2A (0.55) | KMT2ANPSR1POLBHTTL3MBTL1 | |
| SCHEMBL503436 | 1.00 | KMT2A (0.55) | KMT2ANPSR1POLBHTTL3MBTL1 | |
| SCHEMBL11081241 | 0.85 | CA12 (0.47) | KMT2ANPSR1POLBHTTL3MBTL1 | |
| SCHEMBL2461228 | 0.85 | KDM4E (0.50) | KMT2ANPSR1POLBHTTL3MBTL1 | |
| SCHEMBL2461230 | 0.85 | KDM4E (0.50) | KMT2ANPSR1POLBHTTL3MBTL1 | |
| SCHEMBL4697541 | 0.85 | FABP4 (0.48) | KMT2ANPSR1POLBHTTL3MBTL1 | |
| SCHEMBL1354214 | 0.85 | PTGS2 (0.55) | TSHRBLMFABP4FABP5LMNA | |
| SCHEMBL14800030 | 0.85 | PTGS2 (0.55) | TSHRBLMFABP4FABP5LMNA | |
| SCHEMBL5171115 | 0.85 | PTGS2 (0.55) | TSHRBLMFABP4FABP5LMNA | |
| SCHEMBL13170107 | 0.84 | POLB (0.49) | KMT2ANPSR1POLBHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3196185-B1 | ASYMMETRICAL HYDROGENATION REACTION OF KETONIC ACID COMPOUND | ZHEJIANG JIUZHOU PHARMA SCIENCE & TECH CO LTD (CN) | 2019-06-12 | — | — | EP | disclosed |
| US-20170260119-A1 | Asymmetrical hydrogenation reaction of ketonic acid compound | ZHEJIANG JIUZHOU PHARMA SCIENCE&TECHNOLOGY CO LTD (CN) | 2017-09-14 | — | — | US | disclosed |
| US-20170260119-A1 | Asymmetrical hydrogenation reaction of ketonic acid compound | ZHEJIANG JIUZHOU PHARMA SCIENCE&TECHNOLOGY CO LTD (CN) | 2017-09-14 | — | — | US | disclosed |
| EP-3196185-A1 | ASYMMETRICAL HYDROGENATION REACTION OF KETONIC ACID COMPOUND | Zhejiang Jiuzhou Pharma Science & Technology Co., Ltd. (CN) | 2017-07-26 | — | — | EP | disclosed |
| US-6921758-B2 | Amino acid derivatives | ASTRAZENECA AB (SE) | 2005-07-26 | — | — | US | disclosed |
| US-20040087647-A1 | NEW AMINO ACID DERIVATIVES | ASTRAZENECA AB | 2004-05-06 | — | — | US | disclosed |
| US-6617320-B2 | Protease inhibitor; anticoagulants | ASTRAZENECA AB (SE) | 2003-09-09 | — | — | US | disclosed |
| EP-0836615-B1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | ASTRAZENECA AB (SE) | 2003-04-23 | — | — | EP | disclosed |
| US-20020042396-A1 | Amino acid derivatives | ASTRA AB | 2002-04-11 | — | — | US | disclosed |
| US-6337343-B1 | TREATMENT OF THROMBOSIS WITH ANTICOAGULANTS | ASTRAZENECA AB (SE) | 2002-01-08 | — | — | US | disclosed |
| EP-0836615-A1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | Astra Aktiebolag (SE) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002284-A1 | NEW THROMBIN INHIBITORS, THEIR PREPARATION AND USE | ASTRA AKTIEBOLAG (SE) | 1997-01-23 | — | — | WO | disclosed |
| US-4297489-A | CEPHALOSPORINS | BRISTOL-MYERS COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| US-4172196-A | CEPHALOSPORINS | BRISTOL-MYERS COMPANY (US) | 1979-10-23 | — | — | US | disclosed |
| US-4112228-A | BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-3985738-A | ANTIBACTERIAL AGENTS | BRISTOL-MYERS COMPANY (US) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260119-A1 | Asymmetrical hydrogenation reaction of ketonic acid compound | KHK, PKLR, BCKDK | KMT2A 1275/4885NPSR1 3168/4885POLB 2272/4885 |
| US-20020042396-A1 | Amino acid derivatives | F2, SERPINC1, ARGLU1 | KMT2A 2405/4885NPSR1 361/4885POLB 1972/4885 |
| US-20040087647-A1 | NEW AMINO ACID DERIVATIVES | F2, ANPEP, PEPD | KMT2A 2873/4885NPSR1 309/4885POLB 2523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.