Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 7/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 6/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 6/20 | 0.48 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696831 | 0.90 | TPSAB1 (0.39) | TPSAB1TPSD1TPSG1P2RX4CASP3 | |
| SCHEMBL4698784 | 0.85 | TPSAB1 (0.44) | TPSAB1TPSD1TPSG1HRH3ALDH1A1 | |
| SCHEMBL4697341 | 0.83 | TPSAB1 (0.58) | TPSAB1TPSD1TPSG1ASAH1P2RX4 | |
| SCHEMBL4697345 | 0.83 | TPSAB1 (0.58) | TPSAB1TPSD1TPSG1ASAH1P2RX4 | |
| SCHEMBL3339780 | 0.82 | TPSAB1 (0.60) | TPSAB1TPSD1TPSG1ALDH1A1MAPT | |
| SCHEMBL3335635 | 0.78 | TPSAB1 (0.41) | TPSAB1TPSD1TPSG1CASP3 | |
| SCHEMBL3336566 | 0.77 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1ALDH1A1NPSR1 | |
| SCHEMBL3336069 | 0.77 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1ALDH1A1NPSR1 | |
| SCHEMBL3333598 | 0.76 | TPSAB1 (0.51) | TPSAB1TPSD1TPSG1ALDH1A1RAB9A | |
| SCHEMBL3336619 | 0.72 | TPSAB1 (0.48) | TPSAB1TPSD1TPSG1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871741-A2 | SUBSTITUTED AZETIDINONES | Daiamed, Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006108039-A2 | SUBSTITUTED AZETIDINONES | DAIAMED, INC. (US) | 2006-10-12 | — | — | WO | disclosed |