Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 7/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 7/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 7/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696831 | 0.87 | TPSAB1 (0.39) | TPSAB1TPSD1TPSG1F2EPHX2 | |
| SCHEMBL4697607 | 0.85 | TPSAB1 (0.48) | TPSAB1TPSD1TPSG1F2HRH3 | |
| SCHEMBL3338244 | 0.82 | CMA1 (0.39) | TPSAB1TPSD1TPSG1NPC1EPHX1 | |
| SCHEMBL4696612 | 0.75 | TPSAB1 (0.41) | TPSAB1TPSD1TPSG1F2PRSS1 | |
| SCHEMBL3336619 | 0.71 | TPSAB1 (0.48) | TPSAB1TPSD1TPSG1ALDH1A1ALOX12 | |
| SCHEMBL4697341 | 0.70 | TPSAB1 (0.58) | TPSAB1TPSD1TPSG1EPHX2 | |
| SCHEMBL4697345 | 0.70 | TPSAB1 (0.58) | TPSAB1TPSD1TPSG1EPHX2 | |
| SCHEMBL3338358 | 0.69 | CMA1 (0.40) | F2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4696810 | 0.68 | FOLH1 (0.41) | TPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL4694722 | 0.67 | TAAR1 (0.36) | TPSAB1ALDH1A1TAAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871741-A2 | SUBSTITUTED AZETIDINONES | Daiamed, Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006108039-A2 | SUBSTITUTED AZETIDINONES | DAIAMED, INC. (US) | 2006-10-12 | — | — | WO | disclosed |