Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520677 | 0.88 | MAPT (0.59) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1520681 | 0.88 | MAPT (0.59) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| Water SCHEMBL6576232 | 0.87 | MAPT (0.58) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL7750438 | 0.84 | MAPT (0.60) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL13611411 | 0.84 | MAPT (0.70) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL7750442 | 0.84 | MAPT (0.60) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL4698071 | 0.84 | NPC1 (0.61) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| Acetic Acid SCHEMBL915945 | 0.81 | MAPT (0.61) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| Acetic Acid SCHEMBL915943 | 0.81 | MAPT (0.61) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL19449726 | 0.81 | MAPT (0.63) | MAPTNPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | claimed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |