SCHEMBL469797

SCHEMBL469797

N#CCN(CC#N)c1nc(N(CC#N)CC#N)nc(N(CC#N)CC#N)n1

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CRHR1 P34998 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL427141 0.88 TSHR (0.38) TSHRTDP1MAPTSMN1; SMN2
SCHEMBL11776698 0.83 ALDH1A1 (0.36) TSHRTDP1MAPTSMN1; SMN2ALDH1A1
SCHEMBL469847 0.72 MAPT (0.48) TSHRTDP1MAPTSMN1; SMN2CRHR1
SCHEMBL427149 0.64 MAPT (0.41) TSHRTDP1MAPTSMN1; SMN2CRHR1
SCHEMBL9335759 0.60 MAOB (0.41) TSHRMAPTALDH1A1
SCHEMBL11494179 0.58 CYP1A2 (0.53) TDP1ALDH1A1
Water SCHEMBL10884100 0.58 CYP1A2 (0.53) TDP1ALDH1A1
SCHEMBL59753 0.58 CYP1A2 (0.53) TDP1ALDH1A1
SCHEMBL25245 0.58 SLC29A1 (0.34) TSHRTDP1MAPTSMN1; SMN2
SCHEMBL11549049 0.56 CYP1A2 (0.50) TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012033607-A1 METHODS OF REMOVING CARBON DIOXIDE AND SORBENTS FOR SAME BATTELLE ENERGY ALLIANCE, LLC (US) 2012-03-15 WO disclosed