SCHEMBL469847

SCHEMBL469847

N#CCCN(CCC#N)c1nc(N(CCC#N)CCC#N)nc(N(CCC#N)CCC#N)n1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TSHR P16473 2/20 0.44
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 4/20 0.42
TDP1 Q9NUW8 2/20 0.41
CRHR1 P34998 3/20 0.40
LCK P06239 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL427149 0.89 MAPT (0.41) MAPTSMN1; SMN2TSHRMAPK1ALDH1A1
SCHEMBL9393689 0.86 TSHR (0.39) MAPTSMN1; SMN2TSHRMAPK1ALDH1A1
SCHEMBL8418660 0.85 CRHR1 (0.52) MAPTSMN1; SMN2TSHRMAPK1ALDH1A1
SCHEMBL31379937 0.80 ALDH1A1 (0.50) TSHRALDH1A1CRHR1
SCHEMBL9389686 0.80 TSHR (0.35) MAPTSMN1; SMN2TSHRMAPK1ALDH1A1
SCHEMBL10731367 0.75 ALDH1A1 (0.38) MAPTSMN1; SMN2TSHRMAPK1ALDH1A1
SCHEMBL469797 0.72 TSHR (0.44) MAPTSMN1; SMN2TSHRALDH1A1TDP1
SCHEMBL27698970 0.66 TSHR (0.42) TSHRMAPK1ALDH1A1
SCHEMBL9055798 0.64 ALDH1A1 (0.50) TSHRMAPK1ALDH1A1TDP1LCK
SCHEMBL65032 0.64 LCK (0.62) TSHRMAPK1ALDH1A1TDP1LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012033607-A1 METHODS OF REMOVING CARBON DIOXIDE AND SORBENTS FOR SAME BATTELLE ENERGY ALLIANCE, LLC (US) 2012-03-15 WO disclosed