Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | TACR1 | P25103 | 2/20 | 0.63 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | GRK5 | P34947 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2439744 | 0.91 | KDM4E (0.62) | KDM4EALDH1A1GAALMNATACR1 | |
| SCHEMBL11747882 | 0.85 | SIGMAR1 (0.56) | KDM4EALDH1A1GAALMNATACR1 | |
| SCHEMBL6407334 | 0.84 | CYP2D6 (0.54) | KDM4EALDH1A1GAALMNATACR1 | |
| SCHEMBL4244138 | 0.84 | ALDH1A1 (0.97) | KDM4EALDH1A1GAALMNAFAAH | |
| SCHEMBL30341002 | 0.83 | ALDH1A1 (1.00) | KDM4EALDH1A1GAALMNAFAAH | |
| SCHEMBL4235961 | 0.83 | ALDH1A1 (1.00) | KDM4EALDH1A1GAALMNAFAAH | |
| SCHEMBL5577937 | 0.81 | KDM4E (0.74) | KDM4EALDH1A1GAALMNAFAAH | |
| SCHEMBL4145765 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1TACR1FAAHSIGMAR1 | |
| SCHEMBL8108271 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1TACR1FAAHSIGMAR1 | |
| SCHEMBL2093612 | 0.80 | KDM4E (0.72) | KDM4EALDH1A1GAALMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486489-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2016-04-27 | — | — | EP | disclosed |
| EP-1486489-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2016-04-27 | — | — | EP | disclosed |
| EP-1516874-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2015-08-19 | — | — | EP | disclosed |
| EP-1516874-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2015-08-19 | — | — | EP | disclosed |
| EP-1204643-B1 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2008-06-04 | — | — | EP | disclosed |
| EP-1204643-B1 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2008-06-04 | — | — | EP | disclosed |
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-7034035-B2 | Fungicidal mono-, bi-, and tri-cycloheteroalkyl amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2006-04-25 | — | — | US | disclosed |
| EP-1234824-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234823-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234826-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234825-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234827-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1204643-A2 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | Dow AgroSciences LLC (US) | 2002-05-15 | — | — | EP | disclosed |
| EP-1196388-A2 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | Dow AgroSciences LLC (US) | 2002-04-17 | — | — | EP | disclosed |
| US-6355660-B1 | HETEROCYCLIC FUNGICIDES SUBSTITUTED WITH AMIDE GROUPS | DOW AGROSCIENCES LLC | 2002-03-12 | — | — | US | disclosed |
| WO-2001014339-A2 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2001-03-01 | — | — | WO | disclosed |
| WO-2001005769-A2 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2001-01-25 | — | — | WO | disclosed |