Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | GCGR | P47871 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697896 | 0.91 | LMNA (0.61) | ALDH1A1LMNAF2GCGRMEN1 | |
| SCHEMBL4697902 | 0.91 | LMNA (0.61) | ALDH1A1LMNAF2GCGRMEN1 | |
| SCHEMBL4698577 | 0.89 | MAPT (0.58) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4698447 | 0.89 | MAPT (0.58) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL17561003 | 0.88 | MAPT (0.56) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4698396 | 0.81 | GRIN2D (0.58) | ALDH1A1LMNAF2GCGRMEN1 | |
| SCHEMBL4698601 | 0.78 | MAPT (0.50) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4698606 | 0.78 | MAPT (0.50) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL10783548 | 0.77 | LMNA (0.60) | ALDH1A1LMNAF2GCGRMEN1 | |
| SCHEMBL7748696 | 0.76 | MAPT (0.55) | ALDH1A1LMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | claimed |