Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4703865 | 0.91 | THRB (0.46) | THRBHSD17B10HPGDSIRT2SIRT1 | |
| SCHEMBL4702405 | 0.89 | THRB (0.45) | THRBHSD17B10HPGDSIRT2SIRT1 | |
| SCHEMBL4698571 | 0.85 | THRB (0.41) | THRBHSD17B10HPGDSIRT2SIRT1 | |
| SCHEMBL4701536 | 0.85 | THRB (0.43) | THRBHSD17B10HPGDSIRT2SIRT1 | |
| SCHEMBL4699188 | 0.83 | THRB (0.42) | THRBHSD17B10HPGDSIRT2SIRT1 | |
| SCHEMBL4699907 | 0.83 | CRBN (0.44) | THRBHSD17B10HPGDSIRT2SIRT1 | |
| SCHEMBL4702409 | 0.83 | THRB (0.44) | THRBHSD17B10HPGDSMN1; SMN2PTGER4 | |
| SCHEMBL4698515 | 0.82 | HPGD (0.44) | THRBHSD17B10HPGDSIRT2SIRT1 | |
| SCHEMBL4698489 | 0.81 | HPGD (0.43) | THRBHSD17B10HPGDSIRT2SIRT1 | |
| SCHEMBL2652331 | 0.81 | FGFR1 (0.54) | THRBHPGDSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615896-B1 | NOVEL BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2008-04-23 | — | — | EP | claimed |