Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698935 | 0.76 | BCHE (0.40) | — | |
| SCHEMBL4748341 | 0.71 | ITGB1 (0.31) | — | |
| SCHEMBL1786399 | 0.68 | ALOX5AP (0.41) | — | |
| SCHEMBL12607291 | 0.67 | AURKA (0.45) | — | |
| SCHEMBL12607292 | 0.67 | AURKA (0.45) | — | |
| SCHEMBL1786801 | 0.66 | AURKA (0.35) | — | |
| SCHEMBL12607272 | 0.66 | CHEK1 (0.43) | — | |
| SCHEMBL12607276 | 0.66 | CHEK1 (0.43) | — | |
| Formic Acid SCHEMBL1787399 | 0.65 | ALOX5AP (0.38) | — | |
| SCHEMBL3124995 | 0.64 | MERTK (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966218-A1 | NOVEL, CYCLIC SUBSTITUTED FUROPYRIMIDINE DERIVATIVES AND USE THEREOF FOR TREATING CARDIOVASCULAR DISEASES | Bayer HealthCare AG (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007079861-A1 | NOVEL, CYCLIC SUBSTITUTED FUROPYRIMIDINE DERIVATIVES AND USE THEREOF FOR TREATING CARDIOVASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2007-07-19 | — | — | WO | disclosed |