Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750646 | 0.86 | MERTK (0.36) | MERTK | |
| SCHEMBL4750933 | 0.77 | KDM4E (0.41) | MERTK | |
| SCHEMBL4698939 | 0.71 | EDNRB (0.32) | — | |
| SCHEMBL4698935 | 0.69 | BCHE (0.40) | — | |
| SCHEMBL1786801 | 0.66 | AURKA (0.35) | — | |
| SCHEMBL27657898 | 0.64 | CYP2D6 (0.43) | — | |
| SCHEMBL4748527 | 0.63 | AURKA (0.46) | MERTK | |
| SCHEMBL4699368 | 0.63 | AURKA (0.46) | MERTK | |
| SCHEMBL4698505 | 0.63 | AURKA (0.46) | MERTK | |
| SCHEMBL4697193 | 0.61 | KDM4E (0.47) | MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131859-A2 | USE OF CYCLICALLY SUBSTITUTED FUROPYRIMIDINE DERIVATIVES FOR TREATING PULMONARY ARTERIAL HYPERTONIA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-11-06 | — | — | WO | disclosed |