Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.63 |
| ▸ | RXRB | P28702 | 2/20 | 0.63 |
| ▸ | RXRG | P48443 | 2/20 | 0.63 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503308 | 0.94 | PLA2G4B (0.58) | RXRARXRBRXRGPLA2G4BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2528810 | 0.93 | PLA2G4B (0.56) | RXRARXRBRXRGPLA2G4BSMN1; SMN2 | |
| SCHEMBL11969487 | 0.86 | FFAR1 (0.64) | FFAR1 | |
| SCHEMBL4212932 | 0.84 | RXRA (0.69) | RXRARXRBRXRGABCC4LMNA | |
| 3-Methylbutanoic Acid SCHEMBL6891960 | 0.83 | SMN1; SMN2 (0.56) | RXRARXRBRXRGPLA2G4BSMN1; SMN2 | |
| SCHEMBL469923 | 0.83 | FFAR1 (0.69) | LMNAFFAR1FFAR4L3MBTL1 | |
| SCHEMBL9000228 | 0.82 | PLA2G4B (0.79) | LMNATSHRPLA2G4BSMN1; SMN2ALDH1A1 | |
| SCHEMBL11850238 | 0.82 | ABCC4 (0.58) | RXRARXRBRXRGABCC4LMNA | |
| SCHEMBL4217510 | 0.81 | KDM4E (0.68) | RXRARXRBRXRGABCC4LMNA | |
| SCHEMBL10715195 | 0.81 | PTPN11 (0.49) | RXRARXRBRXRGGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120214782-A1 | New compounds, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-08-23 | — | — | US | disclosed |
| WO-2012032014-A1 | ETHYNE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214782-A1 | New compounds, pharmaceutical compositions and uses thereof | ABCG2, PGA5, PDE6G | RXRA 1513/4885RXRB 1663/4885RXRG 1229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.