Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699217 | 1.00 | MIF (0.56) | MIFMMP1MMP2MMP9MAPT | |
| SCHEMBL4702924 | 0.82 | LMNA (0.53) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL4700187 | 0.82 | MAPT (0.60) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL4700007 | 0.82 | MAPT (0.60) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| Iodide SCHEMBL11584757 | 0.80 | MAPT (0.46) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| Iodide SCHEMBL11584755 | 0.80 | MAPT (0.46) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| Iodide SCHEMBL11297268 | 0.79 | CYP2C19 (0.48) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL23709431 | 0.79 | MEN1 (0.66) | MIFMAPTKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL17560945 | 0.78 | MEN1 (0.63) | MIFMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11582865 | 0.76 | CYP1A2 (0.68) | MAPTKMT2AMEN1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | claimed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |