Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.60 |
| ▸ | MEN1 | O00255 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700187 | 1.00 | MAPT (0.60) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL4699516 | 0.88 | MAPT (0.74) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL4699811 | 0.88 | MAPT (0.74) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL19449716 | 0.83 | CTDSP1 (0.71) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL4699223 | 0.82 | MIF (0.56) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL4699217 | 0.82 | MIF (0.56) | MAPTMEN1KMT2AHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL17560817 | 0.81 | CTDSP1 (0.69) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL4702924 | 0.76 | LMNA (0.53) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL4700011 | 0.76 | MAPT (0.59) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL29662955 | 0.75 | MEN1 (0.62) | MAPTMEN1KMT2AALDH1A1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | claimed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |