Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | KRAS | P01116 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465522 | 0.79 | CNR2 (0.62) | CNR2USP30MGLLPDE2A | |
| SCHEMBL487499 | 0.78 | KDM4E (0.45) | CNR2USP30P2RX7KRASPDE2A | |
| SCHEMBL23901483 | 0.77 | USP30 (0.45) | CNR2USP30P2RX7KRASCCR5 | |
| SCHEMBL4462669 | 0.77 | CNR2 (0.60) | CNR2USP30MGLLPDE2A | |
| SCHEMBL4730362 | 0.74 | USP30 (0.55) | CNR2USP30TSHRPDE2A | |
| SCHEMBL4730357 | 0.74 | USP30 (0.55) | CNR2USP30TSHRPDE2A | |
| SCHEMBL4699677 | 0.74 | CNR2 (0.48) | CNR2USP30PDE2A | |
| SCHEMBL14413642 | 0.73 | USP30 (0.54) | CNR2USP30TSHRPDE2A | |
| SCHEMBL23901474 | 0.72 | SPR (0.48) | CNR2USP30P2RX7KRASPDE2A | |
| SCHEMBL25453440 | 0.72 | USP30 (0.54) | CNR2USP30TSHRPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |