Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 5/20 | 0.33 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457376 | 0.75 | TTK (0.58) | ERN1 | |
| SCHEMBL456366 | 0.72 | ERN1 (0.34) | ERN1 | |
| SCHEMBL456669 | 0.71 | HRH4 (0.41) | PI4KBPI4KAHRH4ALDH1A1LMNA | |
| SCHEMBL455915 | 0.70 | SCN5A (0.42) | ALDH1A1ERN1SMN1; SMN2 | |
| SCHEMBL457647 | 0.70 | ERN1 (0.43) | ERN1 | |
| SCHEMBL22855371 | 0.70 | MAPT (0.40) | L3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL470155 | 0.69 | TNF (0.46) | ALDH1A1LMNAERN1SMN1; SMN2MAPK1 | |
| SCHEMBL456990 | 0.69 | TNF (0.46) | ALDH1A1LMNAERN1SMN1; SMN2MAPK1 | |
| SCHEMBL456397 | 0.68 | TNF (0.43) | ALDH1A1LMNAERN1SMN1; SMN2MAPK1 | |
| SCHEMBL455120 | 0.68 | TTK (0.36) | PI4KBPI4KAERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255100-B2 | Substituted imidazopyridazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-09 | — | — | US | disclosed |
| EP-2614063-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER IP GMBH (DE) | 2016-01-13 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |