Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4702275 | 0.99 | CRHR1 (0.41) | CRHR1NPY1R | |
| SCHEMBL7059971 | 0.81 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL4702330 | 0.80 | CRHR1 (0.41) | CRHR1NPY1R | |
| SCHEMBL4700572 | 0.80 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL3366185 | 0.79 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL6024733 | 0.79 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL3364016 | 0.79 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL3839128 | 0.77 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL3364753 | 0.76 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL3364574 | 0.76 | CRHR1 (0.50) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569911-B1 | INDAZOLE DERIVATIVES AS CRF ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-02 | — | — | EP | claimed |