Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700622 | 1.00 | CRHR1 (0.33) | CRHR1BRD9BRD7 | |
| SCHEMBL4700615 | 1.00 | CRHR1 (0.33) | CRHR1BRD9BRD7 | |
| Hydrochloric Acid SCHEMBL4702286 | 0.99 | CRHR1 (0.32) | CRHR1BRD9BRD7 | |
| Hydrochloric Acid SCHEMBL4702283 | 0.99 | CRHR1 (0.32) | CRHR1BRD9BRD7 | |
| Hydrochloric Acid SCHEMBL4698818 | 0.99 | CRHR1 (0.32) | CRHR1BRD9BRD7 | |
| SCHEMBL4700237 | 0.80 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL4700236 | 0.80 | CRHR1 (0.46) | CRHR1 | |
| Hydrochloric Acid SCHEMBL4698197 | 0.79 | CRHR1 (0.46) | CRHR1 | |
| Hydrochloric Acid SCHEMBL4702917 | 0.79 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL3362436 | 0.79 | BRD9 (0.37) | CRHR1BRD9BRD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569911-B1 | INDAZOLE DERIVATIVES AS CRF ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-02 | — | — | EP | claimed |