SCHEMBL470078

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15086668	0.88	NPC1 (0.37)	NPC1RAB9AIDH1KCNH2GRIN2B
	SCHEMBL15086669	0.87	NPC1 (0.41)	NPC1RAB9AIDH1KCNH2GRIN2B
	SCHEMBL469883	0.84	NPC1 (0.35)	NPC1RAB9AIDH1MAPK8MAPK9
	SCHEMBL469885	0.83	BRD4 (0.37)	NPC1RAB9ABRD4KMT2A
	SCHEMBL513374	0.79	NPC1 (0.39)	NPC1RAB9AMAPK8MAPK9LMNA
	SCHEMBL510530	0.79	MAPK8 (0.36)	MAPK8MAPK9LMNAHTTSMN1; SMN2
	SCHEMBL15935632	0.76	PDE2A (0.38)	LMNAPOLBPDE2AHPGDTDP2
	SCHEMBL15935619	0.75	ANPEP (0.38)	CREBBP
	SCHEMBL18131570	0.75	MAPT (0.41)	LMNAPOLBCREBBPHPGDMEN1
	SCHEMBL919414	0.75	KMT2A (0.37)	MAPK8MAPK9LMNAPOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.