Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 15/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470204 | 0.92 | TTK (0.55) | TTKCSF1RCYP3A4FYN | |
| SCHEMBL15555121 | 0.92 | TTK (0.54) | TTKCYP3A4FYN | |
| SCHEMBL10279719 | 0.91 | TTK (0.53) | TTKCYP3A4 | |
| SCHEMBL17590099 | 0.88 | TTK (0.53) | TTKCSF1RCYP3A4 | |
| SCHEMBL17590100 | 0.87 | TTK (0.58) | TTKCSF1RCYP3A4FYN | |
| SCHEMBL470067 | 0.86 | TTK (0.55) | TTKCSF1RCYP3A4FYN | |
| SCHEMBL469990 | 0.86 | TTK (0.51) | TTKFYN | |
| SCHEMBL17425418 | 0.86 | TTK (0.54) | TTKFYN | |
| SCHEMBL17416403 | 0.85 | TTK (0.63) | TTKCYP3A4 | |
| SCHEMBL470065 | 0.85 | TTK (0.49) | TTKHSP90AA1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255100-B2 | Substituted imidazopyridazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-09 | — | — | US | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |