Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 16/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15554683 | 0.92 | TTK (0.56) | TTKCYP3A4FYN | |
| SCHEMBL470099 | 0.92 | TTK (0.53) | TTKCSF1RCYP3A4FYN | |
| SCHEMBL10279277 | 0.91 | TTK (0.55) | TTKCYP3A4 | |
| SCHEMBL17416394 | 0.91 | TTK (0.66) | TTKCYP3A4 | |
| SCHEMBL17590100 | 0.88 | TTK (0.58) | TTKCSF1RCYP3A4SCN9AFYN | |
| SCHEMBL470067 | 0.88 | TTK (0.55) | TTKCSF1RCYP3A4SCN9AFYN | |
| SCHEMBL10279540 | 0.87 | TTK (0.69) | TTKFYN | |
| SCHEMBL17590099 | 0.86 | TTK (0.53) | TTKCSF1RCYP3A4SCN9A | |
| SCHEMBL17590109 | 0.86 | TTK (0.56) | TTKFYN | |
| SCHEMBL470084 | 0.86 | TTK (0.64) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255100-B2 | Substituted imidazopyridazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-09 | — | — | US | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |