Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 13/20 | 0.41 |
| ▸ | CPB1 | P15086 | 5/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13256665 | 0.87 | CPB2 (0.41) | CPB2CPB1NAMPTTSHRCYP2C19 | |
| SCHEMBL13239683 | 0.85 | ALDH1A1 (0.38) | CPB2CPB1 | |
| SCHEMBL2328448 | 0.80 | ALDH1A1 (0.44) | CPB2CPB1 | |
| SCHEMBL26923675 | 0.77 | CPB2 (0.49) | CPB2CPB1 | |
| SCHEMBL1789627 | 0.74 | CYP2C9 (0.58) | CPB2CPB1CYP2C9TSHRCYP2C19 | |
| SCHEMBL12662749 | 0.73 | CPB2 (0.50) | CPB2CPB1PIK3CGPIK3CA | |
| SCHEMBL15065061 | 0.73 | CPB2 (0.47) | CPB2CPB1CYP2C9TSHRCYP2C19 | |
| SCHEMBL12363417 | 0.73 | TSHR (0.43) | CPB2CPB1CYP2C9TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL2259317 | 0.73 | TDP1 (0.59) | CPB2CPB1CYP2C9TSHRCYP2C19 | |
| SCHEMBL31483145 | 0.72 | CPB2 (0.52) | CPB2CPB1PIK3CGNAMPTPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966175-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007068473-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2007-06-21 | — | — | WO | disclosed |