Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 6/20 | 0.38 |
| ▸ | DRD3 | P35462 | 6/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3207675 | 1.00 | IDO1 (0.43) | IDO1DRD2DRD3TRPM8CHRNB2 | |
| SCHEMBL1998256 | 0.84 | IDO1 (0.43) | IDO1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL13490304 | 0.75 | IDO1 (0.41) | IDO1DRD2DRD3TRPM8CHRNB2 | |
| SCHEMBL16466650 | 0.73 | DRD2 (0.46) | IDO1DRD2DRD3TRPM8CHRNB2 | |
| SCHEMBL1922245 | 0.73 | IDO1 (0.42) | IDO1 | |
| SCHEMBL2541173 | 0.73 | IDO1 (0.42) | IDO1 | |
| SCHEMBL30578367 | 0.73 | IDO1 (0.42) | IDO1 | |
| SCHEMBL24482370 | 0.69 | DRD2 (0.42) | IDO1DRD2DRD3TRPM8CHRNB2 | |
| SCHEMBL16033376 | 0.68 | DRD2 (0.44) | IDO1DRD2DRD3TRPM8CHRNB2 | |
| SCHEMBL1154471 | 0.68 | DRD2 (0.44) | IDO1DRD2DRD3TRPM8CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008125230-A2 | INSECTICIDAL DERIVATIVES OF SUBSTITUTED AMINOHETEROCYCLES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | disclosed |
| EP-1977646-A1 | Insecticidal hydroxyethyl thlourea derivatives | Bayer CropScience AG (DE) | 2008-10-08 | — | — | EP | disclosed |
| EP-1977646-A1 | Insecticidal hydroxyethyl thlourea derivatives | Bayer CropScience AG (DE) | 2008-10-08 | — | — | EP | disclosed |