Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789723 | 0.93 | BDKRB1 (0.47) | GSK3BBDKRB1 | |
| SCHEMBL4789665 | 0.93 | BDKRB1 (0.53) | BDKRB1 | |
| SCHEMBL4789977 | 0.89 | BDKRB1 (0.46) | GSK3BBDKRB1 | |
| SCHEMBL6046065 | 0.89 | GSK3B (0.53) | GSK3BBDKRB1 | |
| SCHEMBL4705398 | 0.88 | BDKRB1 (0.59) | BDKRB1 | |
| SCHEMBL4789233 | 0.87 | BDKRB1 (0.47) | BDKRB1 | |
| SCHEMBL4702356 | 0.87 | BDKRB1 (0.56) | GSK3BBDKRB1 | |
| SCHEMBL4789811 | 0.86 | BDKRB1 (0.55) | BDKRB1 | |
| SCHEMBL6046168 | 0.83 | BDKRB1 (0.57) | BDKRB1 | |
| SCHEMBL4790458 | 0.83 | BDKRB1 (0.45) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633348-B1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARM INC (US) | 2008-10-08 | — | — | EP | claimed |