Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.33 |
| ▸ | MAOB | P27338 | 7/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 4/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159710 | 0.82 | TSHR (0.43) | TSHRLMNACYP3A4CYP2D6ELANE | |
| SCHEMBL1587776 | 0.70 | ELANE (0.42) | MAOAMAOBLMNAELANEGAA | |
| SCHEMBL1680374 | 0.67 | ELANE (0.40) | MAOAMAOBTSHRELANE | |
| SCHEMBL14159720 | 0.67 | GAA (0.38) | MAOBTSHRLMNACYP3A4ELANE | |
| SCHEMBL29059754 | 0.66 | MAOA (0.43) | MAOAMAOBTSHRELANE | |
| Hydrochloric Acid SCHEMBL29078695 | 0.66 | MAOA (0.41) | MAOAMAOBLMNAKDM1AELANE | |
| SCHEMBL8704294 | 0.65 | MAOA (0.43) | MAOAMAOBTSHRKDM1AELANE | |
| SCHEMBL18805033 | 0.64 | ELANE (0.42) | MAOAMAOBTSHRLMNAELANE | |
| SCHEMBL27989707 | 0.63 | MAOA (0.40) | MAOAMAOBLMNACYP3A4KDM1A | |
| SCHEMBL7744080 | 0.63 | CYP3A4 (0.38) | TSHRLMNACYP3A4CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486489-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2016-04-27 | — | — | EP | disclosed |
| EP-1516874-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2015-08-19 | — | — | EP | disclosed |
| EP-1516874-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2015-08-19 | — | — | EP | disclosed |
| EP-1204643-B1 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2008-06-04 | — | — | EP | disclosed |
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-7034035-B2 | Fungicidal mono-, bi-, and tri-cycloheteroalkyl amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2006-04-25 | — | — | US | disclosed |
| US-6927225-B2 | Fungicidal 2-pyridyl alkyl amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2005-08-09 | — | — | US | disclosed |
| EP-1516874-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2005-03-23 | — | — | EP | disclosed |
| US-20030022903-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | RICKS MICHAEL J (US) | 2003-01-30 | — | — | US | disclosed |
| US-20030018012-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | RICKS MICHAEL J (US) | 2003-01-23 | — | — | US | disclosed |
| US-20030018052-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | RICKS MICHAEL J (US) | 2003-01-23 | — | — | US | disclosed |
| US-20020177578-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | RICKS MICHAEL J (US) | 2002-11-28 | — | — | US | disclosed |
| EP-1234824-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234825-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234826-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234823-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234827-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6355660-B1 | HETEROCYCLIC FUNGICIDES SUBSTITUTED WITH AMIDE GROUPS | DOW AGROSCIENCES LLC | 2002-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018012-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | CYP4X1, CYP1A1, NAT1 | MAOA 40/4885MAOB 269/4885TSHR 2951/4885 |
| US-20020177578-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | CYP4X1, CYP1A1, NAT1 | MAOA 40/4885MAOB 269/4885TSHR 2951/4885 |
| US-20030022903-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | CYP4X1, NAT1, CYP1A1 | MAOA 42/4885MAOB 263/4885TSHR 3220/4885 |
| US-20030018052-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | NAT1, CYP4X1, CYP1A1 | MAOA 46/4885MAOB 270/4885TSHR 3118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.