Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.42 |
| ▸ | ITGAV | P06756 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.38 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.38 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698663 | 0.89 | GAA (0.47) | ITGB3ITGA2BGAATAS1R3TAS1R1 | |
| SCHEMBL4699846 | 0.88 | GAA (0.45) | ITGB3ITGA2BGAAF2RTAS1R3 | |
| SCHEMBL4702523 | 0.87 | GAA (0.48) | ITGB3ITGA2BGAAF2RTAS1R3 | |
| SCHEMBL4699864 | 0.86 | MAPT (0.44) | ITGB3ITGA2BGAATAS1R3TAS1R1 | |
| SCHEMBL4700412 | 0.86 | RAB9A (0.45) | ITGB3ITGA2BGAAF2RTAS1R3 | |
| SCHEMBL4700843 | 0.85 | GAA (0.47) | ITGB3ITGA2BGAATAS1R3TAS1R1 | |
| SCHEMBL6127212 | 0.83 | POLB (0.46) | ITGB3ITGA2BGAATAS1R3TAS1R1 | |
| SCHEMBL17009347 | 0.83 | POLB (0.46) | ITGB3ITGA2BGAATAS1R3TAS1R1 | |
| SCHEMBL20530282 | 0.83 | POLB (0.46) | ITGB3ITGA2BGAATAS1R3TAS1R1 | |
| SCHEMBL7902080 | 0.83 | GAA (0.42) | ITGB3ITGA2BGAAF2RTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071680-B1 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2008-07-23 | — | — | EP | disclosed |
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | disclosed |