Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 2/20 | 0.39 |
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698663 | 0.91 | GAA (0.47) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL4699846 | 0.86 | GAA (0.45) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL4702523 | 0.86 | GAA (0.48) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL4701718 | 0.85 | ITGB3 (0.45) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL4700412 | 0.85 | RAB9A (0.45) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL4699864 | 0.85 | MAPT (0.44) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL6127212 | 0.82 | POLB (0.46) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL17009347 | 0.82 | POLB (0.46) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL7902080 | 0.82 | GAA (0.42) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL20530282 | 0.82 | POLB (0.46) | GAATAS1R3TAS1R1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071680-B1 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2008-07-23 | — | — | EP | disclosed |
| EP-1071680-A4 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | TEXAS BIOTECHNOLOGY CORP (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | disclosed |
| EP-1071680-A1 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999052898-A1 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1999-10-21 | — | — | WO | disclosed |