Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | BACE1 | P56817 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | TGM1 | P22735 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29796094 | 0.89 | BACE1 (0.48) | MEN1KMT2ABACE1LMNANPSR1 | |
| SCHEMBL470212 | 0.89 | MEN1 (0.51) | MEN1KMT2ABACE1LMNANPSR1 | |
| SCHEMBL470218 | 0.89 | BACE1 (0.48) | MEN1KMT2ABACE1LMNANPSR1 | |
| SCHEMBL457432 | 0.89 | MEN1 (0.51) | MEN1KMT2ABACE1LMNANPSR1 | |
| SCHEMBL2365831 | 0.84 | LMNA (0.50) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL457220 | 0.83 | MAPT (0.52) | MEN1KMT2ALMNANPSR1MAPT | |
| SCHEMBL470197 | 0.81 | MEN1 (0.47) | MEN1KMT2ABACE1LMNANPSR1 | |
| SCHEMBL31129872 | 0.79 | SMARCA2 (0.52) | MEN1KMT2ABACE1LMNAMAPT | |
| SCHEMBL463132 | 0.79 | BACE1 (0.49) | MEN1KMT2ABACE1LMNANPSR1 | |
| SCHEMBL470227 | 0.79 | BACE1 (0.47) | MEN1KMT2ABACE1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033736-A1 | NOVEL PIPERAZINE ANALOGS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-15 | — | — | WO | disclosed |