Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 16/20 | 0.53 |
| ▸ | ERN1 | O75460 | 3/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456811 | 0.93 | TTK (0.53) | TTKERN1FYN | |
| SCHEMBL470017 | 0.84 | TTK (0.46) | TTK | |
| SCHEMBL470248 | 0.82 | ERN1 (0.48) | TTKERN1 | |
| SCHEMBL456264 | 0.79 | TTK (0.51) | TTKERN1FYN | |
| SCHEMBL457290 | 0.76 | TTK (0.43) | TTKERN1 | |
| SCHEMBL459313 | 0.75 | TTK (0.47) | TTKERN1 | |
| SCHEMBL10279503 | 0.75 | TTK (0.50) | TTKFYN | |
| SCHEMBL458247 | 0.74 | TTK (0.61) | TTK | |
| SCHEMBL469994 | 0.73 | FYN (0.47) | TTKFYN | |
| SCHEMBL470169 | 0.73 | TTK (0.45) | TTKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |