Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1689043 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HTTKDM4EMEN1KMT2A | |
| SCHEMBL1688969 | 0.85 | MAPT (0.49) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4699918 | 0.83 | MAPT (0.41) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4166769 | 0.80 | MAPT (0.60) | ALDH1A1HTTKDM4EKMT2AMAPT | |
| SCHEMBL5611660 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HTTMEN1KMT2APOLB | |
| SCHEMBL1689243 | 0.77 | MAPT (0.51) | ALDH1A1HTTKDM4EMEN1KMT2A | |
| SCHEMBL1688905 | 0.77 | MAPT (0.52) | ALDH1A1HTTKDM4EMEN1KMT2A | |
| SCHEMBL4170703 | 0.77 | KDM4E (0.41) | ALDH1A1HTTKDM4EMEN1GFER | |
| SCHEMBL1689010 | 0.76 | MAPT (0.45) | ALDH1A1HTTKDM4EMEN1KMT2A | |
| SCHEMBL5611546 | 0.76 | MAPT (0.43) | ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999132-A1 | AZOLOPYRIMIDINES AS INHIBITORS OF CANNABINOID 1 ACTIVITY | IRM, LLC (BM) | 2008-12-10 | — | — | EP | claimed |
| WO-2007120454-A1 | AZOLOPYRIMIDINES AS INHIBITORS OF CANNABINOID 1 ACTIVITY | IRM LLC (BM) | 2007-10-25 | — | — | WO | claimed |