Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.57 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968429 | 0.88 | DPP4 (0.46) | DPP4USP30RORCMC4RPDE4B | |
| SCHEMBL148144 | 0.83 | RORC (0.49) | DPP4USP30RORCMEN1KMT2A | |
| SCHEMBL148143 | 0.83 | RORC (0.49) | DPP4USP30RORCMEN1KMT2A | |
| SCHEMBL148142 | 0.83 | RORC (0.49) | DPP4USP30RORCMEN1KMT2A | |
| SCHEMBL1725669 | 0.83 | RORC (0.49) | DPP4USP30RORCMEN1KMT2A | |
| SCHEMBL463402 | 0.83 | PDE4B (0.50) | DPP4USP30CYP3A4CYP3A5CNR1 | |
| SCHEMBL463401 | 0.83 | PDE4B (0.50) | DPP4USP30CYP3A4CYP3A5CNR1 | |
| SCHEMBL463400 | 0.83 | PDE4B (0.50) | DPP4USP30CYP3A4CYP3A5CNR1 | |
| SCHEMBL528928 | 0.82 | PDE4B (0.47) | DPP4USP30RORCMC4RPDE4B | |
| SCHEMBL528371 | 0.82 | DPP4 (0.49) | DPP4USP30RORCSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |