Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.69 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30340025 | 1.00 | OPRD1 (0.69) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL29389298 | 1.00 | OPRD1 (0.69) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL3687986 | 0.89 | OPRD1 (0.71) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL12646374 | 0.89 | OPRD1 (0.69) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL18457908 | 0.89 | OPRD1 (0.69) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL31492345 | 0.89 | OPRD1 (0.69) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL12945146 | 0.89 | OPRD1 (0.69) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL17284758 | 0.89 | OPRD1 (0.69) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL6627728 | 0.87 | OPRD1 (0.54) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL3176373 | 0.85 | OPRD1 (0.62) | OPRD1OPRM1OPRK1LMNAPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0911334-B1 | QUINOLINOMORPHINANE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2008-05-21 | — | — | EP | disclosed |
| EP-1203771-A1 | REMEDIES OR PREVENTIVES FOR FREQUENT URINATION OR URINARY INCONTINENCE | TORAY INDUSTRIES, INC. (JP) | 2002-05-08 | — | — | EP | disclosed |
| US-6172078-B1 | PREVENTING WORSENING OF CEREBRAL STROKE; ANTIISCHEMIC AGENTS; BRAIN DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0911334-A1 | QUINOLINOMORPHINANE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1999-04-28 | — | — | EP | disclosed |