Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 11/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10392215 | 0.90 | OPRD1 (0.55) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL4116882 | 0.90 | OPRD1 (0.55) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL12646376 | 0.90 | OPRD1 (0.54) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL17284788 | 0.90 | OPRD1 (0.54) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL7893264 | 0.89 | OPRD1 (0.45) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL10222580 | 0.88 | OPRD1 (0.51) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL17284443 | 0.88 | OPRD1 (0.51) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL10222585 | 0.88 | OPRD1 (0.55) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL17284441 | 0.88 | OPRD1 (0.55) | OPRD1OPRM1OPRK1LMNAPDE4D | |
| SCHEMBL4705017 | 0.87 | OPRD1 (0.69) | OPRD1OPRM1OPRK1LMNAPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894799-B1 | INDOLOMORPHINANE DERIVATIVES AND REMEDIES/PREVENTIVES FOR CEREBRAL DISORDERS | TORAY INDUSTRIES (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-6156762-A | Indolomorphinan derivative and agent for curing and preventing cerebral disorder | TORAY INDUSTRIES, INC. (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0894799-A1 | INDOLOMORPHINANE DERIVATIVES AND REMEDIES/PREVENTIVES FOR CEREBRAL DISORDERS | TORAY INDUSTRIES, INC. (JP) | 1999-02-03 | — | — | EP | disclosed |