Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 5/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | MMP7 | P09237 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL387827 | 1.00 | GPR119 (0.48) | GPR119HPGDRECQLEPHX1NPC1 | |
| SCHEMBL24092369 | 1.00 | GPR119 (0.48) | GPR119HPGDRECQLEPHX1NPC1 | |
| SCHEMBL30478340 | 0.93 | GPR119 (0.46) | GPR119HPGDRECQLEPHX1NPC1 | |
| SCHEMBL25874548 | 0.93 | GPR119 (0.46) | GPR119HPGDRECQLEPHX1NPC1 | |
| SCHEMBL12415378 | 0.87 | NR1H2 (0.43) | GPR119HPGDRECQLEPHX1NPC1 | |
| SCHEMBL2188059 | 0.85 | ALDH1A1 (0.45) | GPR119HPGDEPHX1NPC1ALDH1A1 | |
| SCHEMBL24038580 | 0.84 | GPR119 (0.47) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL384998 | 0.83 | GPR119 (0.44) | GPR119MMP13MMP1MMP3MMP7 | |
| SCHEMBL866117 | 0.83 | GPR119 (0.44) | GPR119MMP13MMP1MMP3MMP7 | |
| SCHEMBL25304410 | 0.82 | GPR119 (0.39) | GPR119HPGDRECQLNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648763-A2 | COMPOUNDS FOR FGFRS INHIBITORS | Cogent Biosciences, Inc. (US) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024151638-A2 | COMPOUNDS FOR FGFRS INHIBITORS | COGENT BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |