Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 4/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4705618 | 0.85 | GAA (0.40) | TAAR1CYP19A1ACHE | |
| SCHEMBL4952650 | 0.81 | TAAR1 (0.50) | TAAR1HRH3DAOIDO1GPR84 | |
| SCHEMBL4951464 | 0.77 | MAPK1 (0.38) | TAAR1CYP19A1ALDH1A1 | |
| SCHEMBL3056983 | 0.74 | TAAR1 (0.59) | TAAR1HRH3DAOIDO1GPR84 | |
| SCHEMBL4953940 | 0.74 | TAAR1 (0.63) | TAAR1HRH3DAOIDO1GPR84 | |
| SCHEMBL4460308 | 0.73 | IDO1 (0.49) | TAAR1DAOIDO1 | |
| SCHEMBL29596752 | 0.73 | TAAR1 (0.74) | TAAR1HRH3DAOIDO1GPR84 | |
| SCHEMBL8096473 | 0.73 | TAAR1 (0.74) | TAAR1HRH3DAOIDO1GPR84 | |
| SCHEMBL21868801 | 0.73 | TAAR1 (0.62) | TAAR1HRH3DAOIDO1GPR84 | |
| SCHEMBL8208663 | 0.72 | TAAR1 (0.52) | TAAR1HRH3DAOIDO1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977754-B1 | WRITABLE AND ERASABLE HIGH-DENSITY OPTICAL STORAGE MEDIA | CIBA SC HOLDING AG (CH) | 2008-01-16 | — | — | EP | disclosed |
| US-5459142-A | Autoimmune disease, atherosclerosis, antiischemic agents and nephritis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-10-17 | — | — | US | disclosed |