Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4705622 | 0.85 | TAAR1 (0.49) | CYP19A1TAAR1ACHE | |
| SCHEMBL5081816 | 0.78 | TAS1R3 (0.42) | MAPTCYP19A1CYP1A2ACHEAOC3 | |
| SCHEMBL4951466 | 0.76 | TP53 (0.39) | MAPTKCNH2CYP19A1TAAR1CYP1A2 | |
| SCHEMBL16960887 | 0.74 | ACHE (0.46) | MAPTCYP19A1TAAR1CYP1A2ACHE | |
| SCHEMBL16959287 | 0.72 | ACHE (0.44) | GAAMAPTCYP19A1TAAR1CYP1A2 | |
| SCHEMBL16954126 | 0.72 | ACP3 (0.44) | MAPTCYP19A1TAAR1CYP1A2ACHE | |
| SCHEMBL9228259 | 0.72 | CYP19A1 (0.53) | KCNH2CYP19A1TAAR1CYP1A2CYP2A6 | |
| SCHEMBL16957877 | 0.72 | ACHE (0.44) | GAAMAPTCYP19A1TAAR1CYP1A2 | |
| SCHEMBL4953940 | 0.71 | TAAR1 (0.63) | KCNH2CYP19A1TAAR1CYP1A2CYP2A6 | |
| SCHEMBL1147908 | 0.71 | ACP3 (0.48) | KCNH2CYP19A1TAAR1CYP2A6ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977754-B1 | WRITABLE AND ERASABLE HIGH-DENSITY OPTICAL STORAGE MEDIA | CIBA SC HOLDING AG (CH) | 2008-01-16 | — | — | EP | disclosed |