Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 2/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27495396 | 0.90 | IDO1 (0.60) | IDO1TDO2TAAR1NPC1RAB9A | |
| SCHEMBL27495003 | 0.77 | MEN1 (0.48) | IDO1TDO2TAAR1KMT2ACNR1 | |
| SCHEMBL15989864 | 0.74 | TAAR1 (0.63) | IDO1TAAR1PNMTAOC3HTR3E | |
| SCHEMBL4705622 | 0.73 | TAAR1 (0.49) | IDO1TAAR1DAO | |
| SCHEMBL4951464 | 0.73 | MAPK1 (0.38) | TAAR1NPC1RAB9AKMT2ACYP3A4 | |
| SCHEMBL12050856 | 0.73 | TAAR1 (0.74) | IDO1TAAR1PNMTAOC3HTR3E | |
| SCHEMBL5103603 | 0.73 | PNMT (0.58) | IDO1TDO2TAAR1NPC1RAB9A | |
| SCHEMBL11563895 | 0.71 | KMT2A (0.54) | IDO1TDO2TAAR1NPC1RAB9A | |
| SCHEMBL11611747 | 0.71 | KMT2A (0.54) | IDO1TDO2TAAR1NPC1RAB9A | |
| SCHEMBL265738 | 0.70 | PNMT (0.70) | IDO1TDO2TAAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247511-B2 | Water plasticized high refractive index polymer for ophthalmic applications | ADVANCED VISION SCIENCE, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| EP-2049923-A2 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | Advanced Vision Science, Inc. (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008013950-A2 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | ADVANCED VISION SCIENCE, INC. (US) | 2008-01-31 | — | — | WO | disclosed |
| US-20070010883-A1 | Water plasticized high refractive index polymer for ophthalmic applications | ADVANCED VISION SCIENCE, INC. | 2007-01-11 | — | — | US | disclosed |