Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 4/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | USP14 | P54578 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4706419 | 0.85 | SLC6A9 (0.44) | SLC6A9HRH3CHRM4CHRM2DPP4 | |
| SCHEMBL4704520 | 0.84 | EGLN2 (0.37) | EGLN2KDM2BHRH3IRAK4 | |
| SCHEMBL22570962 | 0.82 | CHRM4 (0.47) | SLC6A9CHRM4 | |
| SCHEMBL4708143 | 0.82 | ACACB (0.39) | KDM2B | |
| SCHEMBL4759948 | 0.78 | SLC6A9 (0.46) | SLC6A9HRH3KDM1A | |
| SCHEMBL22099636 | 0.76 | NOTUM (0.53) | SLC6A9CHRM4CHRM2DPP4DPP8 | |
| SCHEMBL5213102 | 0.75 | HRH3 (0.50) | SLC6A9HRH3CHRM4 | |
| SCHEMBL4827676 | 0.75 | SLC6A9 (0.43) | SLC6A9USP14CHRM4CHRM2DPP4 | |
| SCHEMBL14437322 | 0.75 | SLC6A9 (0.43) | SLC6A9USP14CHRM4CHRM2DPP4 | |
| SCHEMBL4759950 | 0.74 | USP30 (0.45) | SLC6A9USP14CHRM4CHRM2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979318-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2008-10-15 | — | — | EP | claimed |
| WO-2007089683-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-08-09 | — | — | WO | claimed |