Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15759159 | 0.90 | TP53 (0.41) | ACACBKMT2APOLBKDM4EHTT | |
| SCHEMBL15759209 | 0.87 | TP53 (0.44) | ACACBSLC18A3KDM4EHTTTP53 | |
| SCHEMBL22860586 | 0.87 | HTR6 (0.43) | ACACBKMT2APOLBSLC18A3TP53 | |
| SCHEMBL4707178 | 0.84 | LMNA (0.46) | ACACBPDE7AKDM4EHTTTP53 | |
| SCHEMBL15759177 | 0.83 | TP53 (0.46) | ACACBKMT2APOLBSLC18A3TP53 | |
| SCHEMBL15759180 | 0.83 | ACACB (0.43) | ACACBKDM4ETP53 | |
| SCHEMBL14450221 | 0.83 | ACACB (0.43) | ACACBKDM4ETP53 | |
| SCHEMBL15759160 | 0.82 | TP53 (0.45) | ACACBKMT2APOLBSLC18A3TP53 | |
| SCHEMBL4705699 | 0.82 | SLC6A9 (0.40) | KDM2B | |
| SCHEMBL27004866 | 0.81 | ACACB (0.47) | ACACBPDE7ACCR1CCR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979318-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2008-10-15 | — | — | EP | claimed |
| WO-2007089683-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-08-09 | — | — | WO | claimed |