Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148263 | 0.86 | GPR119 (0.44) | GPR119LMNAMAPTOPRK1ALOX5AP | |
| SCHEMBL148262 | 0.86 | GPR119 (0.44) | GPR119LMNAMAPTOPRK1ALOX5AP | |
| SCHEMBL19454522 | 0.84 | GPR119 (0.43) | GPR119LMNAMAPTOPRK1ALOX5AP | |
| SCHEMBL12506056 | 0.83 | GPR119 (0.59) | GPR119LMNAMAPTOPRK1ALOX5AP | |
| SCHEMBL19450679 | 0.82 | GPR119 (0.50) | GPR119LMNAMAPTOPRK1ALOX5AP | |
| SCHEMBL470543 | 0.81 | GPR119 (0.73) | GPR119LMNAMAPT | |
| SCHEMBL384918 | 0.81 | GPR119 (0.73) | GPR119LMNAMAPT | |
| SCHEMBL388674 | 0.81 | GPR119 (0.73) | GPR119LMNAMAPT | |
| SCHEMBL470537 | 0.80 | GPR119 (0.39) | GPR119LMNAMAPTOPRK1 | |
| SCHEMBL1713467 | 0.79 | GPR119 (0.39) | GPR119LMNAOPRK1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |