Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470787 | 0.81 | GPR119 (0.32) | GPR119 | |
| SCHEMBL470673 | 0.77 | OPRK1 (0.31) | GPR119OPRK1 | |
| SCHEMBL148263 | 0.73 | GPR119 (0.44) | GPR119OPRK1LMNAMAPT | |
| SCHEMBL148262 | 0.73 | GPR119 (0.44) | GPR119OPRK1LMNAMAPT | |
| SCHEMBL12506056 | 0.73 | GPR119 (0.59) | GPR119OPRK1LMNAMAPT | |
| SCHEMBL19454522 | 0.71 | GPR119 (0.43) | GPR119OPRK1LMNAMAPT | |
| SCHEMBL14730194 | 0.68 | OPRK1 (0.40) | GPR119OPRK1LMNA | |
| Hydrochloric Acid SCHEMBL14723194 | 0.68 | SMN1; SMN2 (0.44) | GPR119LMNA | |
| Hydrochloric Acid SCHEMBL14723195 | 0.67 | OPRK1 (0.39) | GPR119OPRK1LMNA | |
| SCHEMBL19454467 | 0.67 | GPR119 (0.66) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |