Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12064733 | 0.88 | MCHR1 (0.44) | MCHR1ACACBACACADPP4KCNH2 | |
| SCHEMBL470554 | 0.87 | MCHR1 (0.43) | MCHR1ACACBDPP4KCNH2DPP8 | |
| SCHEMBL470860 | 0.86 | MCHR1 (0.43) | MCHR1DPP4KCNH2DPP8DPP9 | |
| SCHEMBL470640 | 0.85 | MCHR1 (0.36) | MCHR1ACACBACACAKCNH2GPR119 | |
| SCHEMBL470611 | 0.85 | MCHR1 (0.49) | MCHR1DPP4KCNH2DPP8DPP9 | |
| SCHEMBL12064536 | 0.84 | MCHR1 (0.49) | MCHR1DPP4KCNH2DPP8DPP9 | |
| SCHEMBL470604 | 0.82 | GPR119 (0.49) | MCHR1DPP4KCNH2DPP8DPP9 | |
| SCHEMBL14730362 | 0.81 | DPP4 (0.36) | MCHR1DPP4KCNH2DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL462044 | 0.81 | MCHR1 (0.42) | MCHR1DPP4KCNH2DPP8DPP9 | |
| SCHEMBL470612 | 0.80 | MCHR1 (0.45) | MCHR1DPP4KCNH2DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |