Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | RBP4 | P02753 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 4/20 | 0.34 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12064977 | 0.91 | GPR119 (0.38) | MCHR1NTRK1GPR119RBP4TTR | |
| SCHEMBL470751 | 0.89 | GPR119 (0.38) | MCHR1NTRK1GPR119RBP4TTR | |
| SCHEMBL470485 | 0.88 | GPR119 (0.43) | MCHR1NTRK1GPR119KCNH2RET | |
| SCHEMBL470590 | 0.87 | NTRK1 (0.38) | MCHR1NTRK1GPR119ACACBRBP4 | |
| SCHEMBL470618 | 0.85 | MCHR1 (0.43) | MCHR1GPR119ACACBRBP4TTR | |
| SCHEMBL12064703 | 0.85 | MCHR1 (0.37) | MCHR1NTRK1GPR119KCNH2HDAC6 | |
| SCHEMBL459423 | 0.83 | GPR119 (0.41) | MCHR1NTRK1GPR119RBP4RET | |
| SCHEMBL470475 | 0.83 | GPR119 (0.38) | GPR119ACACBKCNH2EIF2AK4 | |
| SCHEMBL12064704 | 0.82 | GPR119 (0.36) | MCHR1NTRK1GPR119ACACBRET | |
| SCHEMBL458155 | 0.80 | PDE4B (0.43) | MCHR1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |