Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.53 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456972 | 0.87 | GPR119 (0.53) | GPR119GPR183CNR2 | |
| SCHEMBL470755 | 0.86 | GPR119 (0.53) | GPR119GPR183CNR2 | |
| SCHEMBL13186690 | 0.85 | GPR119 (0.46) | GPR119GPR183CNR2 | |
| SCHEMBL470560 | 0.84 | GPR119 (0.55) | GPR119GPR183CNR2 | |
| SCHEMBL470551 | 0.83 | GPR119 (0.51) | GPR119GPR183CNR2 | |
| SCHEMBL470522 | 0.81 | GPR119 (0.50) | GPR119GPR183CNR2 | |
| SCHEMBL12064706 | 0.80 | GPR119 (0.54) | GPR119GPR183 | |
| SCHEMBL1805912 | 0.77 | GPR119 (0.47) | GPR119GPR183 | |
| SCHEMBL458932 | 0.77 | GPR119 (0.53) | GPR119GPR183CNR2 | |
| SCHEMBL387959 | 0.75 | GPR119 (0.64) | GPR119GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |