Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4706550 | 0.93 | MAPT (0.42) | GPR119MAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL389195 | 0.88 | GPR119 (0.63) | GPR119MAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL4758297 | 0.87 | MAPT (0.41) | GPR119MAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL4703579 | 0.84 | GPR174 (0.42) | MAPTALDH1A1MAPK1LMNAL3MBTL1 | |
| SCHEMBL4705303 | 0.84 | GPR119 (0.53) | GPR119MAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL385902 | 0.84 | GPR119 (0.46) | GPR119MAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL5266036 | 0.84 | GPR119 (0.53) | GPR119MAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL389643 | 0.82 | MAPT (0.45) | GPR119MAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL4702867 | 0.82 | GPR119 (0.50) | GPR119MAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL5259360 | 0.82 | GPR119 (0.60) | GPR119MAPTALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606282-B1 | PHENYL- AND PYRIDYLPIPEREIDINYE-DERIVATIVES AS MODULATORS OF GLUCOSE METABOLISM | ARENA PHARM INC (US) | 2008-11-12 | — | — | EP | claimed |