Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 4/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470608 | 0.85 | NTRK1 (0.37) | CKS1BSKP1SKP2RETGPR119 | |
| SCHEMBL470549 | 0.83 | ALOX5AP (0.30) | CKS1BSKP1SKP2 | |
| SCHEMBL12064539 | 0.78 | GPR119 (0.35) | GPR119 | |
| SCHEMBL470805 | 0.74 | DPP4 (0.32) | CKS1BSKP1SKP2RET | |
| SCHEMBL470672 | 0.72 | ACACB (0.35) | — | |
| SCHEMBL470699 | 0.72 | DPP4 (0.35) | — | |
| SCHEMBL470590 | 0.71 | NTRK1 (0.38) | RETGPR119 | |
| SCHEMBL470564 | 0.71 | NTRK1 (0.36) | RETGPR119 | |
| SCHEMBL457627 | 0.71 | DPP4 (0.34) | CKS1BSKP1SKP2RETGPR119 | |
| SCHEMBL470864 | 0.71 | GPR119 (0.30) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |