Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 10/20 | 0.35 |
| ▸ | BRD2 | P25440 | 7/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 7/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14343958 | 0.84 | KDM4E (0.42) | KDM4EPKMPOLBEDNRBEDNRA | |
| SCHEMBL4708275 | 0.84 | KDM4E (0.50) | KDM4EPKMPOLBTP53BRD4 | |
| SCHEMBL4201621 | 0.84 | KDM4E (0.38) | KDM4EPKMPOLBNPC1RAB9A | |
| SCHEMBL4186012 | 0.84 | KDM4E (0.38) | KDM4EPKMPOLBNPC1RAB9A | |
| SCHEMBL4203956 | 0.83 | POLB (0.38) | KDM4EPKMPOLBNPC1RAB9A | |
| SCHEMBL4708923 | 0.79 | KDM4E (0.45) | KDM4EPKMPOLBMAPT | |
| Hydrochloric Acid SCHEMBL4709828 | 0.75 | PRF1 (0.39) | POLBNPC1RAB9AMAPTTP53 | |
| SCHEMBL4709029 | 0.74 | KDM4E (0.49) | KDM4EPKMPOLBMAPTTP53 | |
| SCHEMBL4709060 | 0.73 | KDM4E (0.42) | KDM4EPKMPOLBMAPTTP53 | |
| SCHEMBL4708309 | 0.72 | LMNA (0.41) | KDM4EPKMPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |