Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19434409 | 1.00 | GPR119 (0.46) | GPR119ALOX5APCCR1LMNAMAPT | |
| SCHEMBL470597 | 0.90 | GPR119 (0.45) | GPR119ALOX5APCCR1LMNAMAPT | |
| SCHEMBL470684 | 0.87 | GPR119 (0.47) | GPR119ALOX5APLMNAMAPT | |
| SCHEMBL19457227 | 0.85 | GPR119 (0.42) | GPR119ALOX5APCCR1LMNAMAPT | |
| SCHEMBL19450516 | 0.83 | GPR119 (0.40) | GPR119ALOX5APLMNAMAPTKCNH2 | |
| SCHEMBL470649 | 0.80 | GPR119 (0.40) | GPR119ALOX5APKCNH2EGFRKCNE1 | |
| SCHEMBL19450679 | 0.80 | GPR119 (0.50) | GPR119ALOX5APLMNAMAPT | |
| SCHEMBL470543 | 0.78 | GPR119 (0.73) | GPR119LMNAMAPTKCNH2 | |
| SCHEMBL384918 | 0.78 | GPR119 (0.73) | GPR119LMNAMAPTKCNH2 | |
| SCHEMBL388674 | 0.78 | GPR119 (0.73) | GPR119LMNAMAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |