Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.44 |
| ▸ | DPP4 | P27487 | 12/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12064536 | 0.85 | MCHR1 (0.49) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL120059 | 0.81 | GPR119 (0.47) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL121289 | 0.77 | MCHR1 (0.44) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL470611 | 0.77 | MCHR1 (0.49) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL12064746 | 0.77 | MCHR1 (0.44) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL462518 | 0.75 | DPP4 (0.43) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL149798 | 0.73 | GPR119 (0.43) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL462138 | 0.72 | MCHR1 (0.53) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL470665 | 0.72 | GPR119 (0.40) | KCNH2GPR119 | |
| SCHEMBL470618 | 0.72 | MCHR1 (0.43) | MCHR1DPP4DPP8DPP9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |