Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459659 | 0.89 | CA1 (0.34) | TNFRSF1ACA1CA2 | |
| SCHEMBL458095 | 0.77 | ALDH1A1 (0.36) | TNFRSF1ACA1CA2 | |
| SCHEMBL459987 | 0.73 | MAOB (0.34) | PPARG | |
| SCHEMBL12585362 | 0.73 | TNFRSF1A (0.34) | TNFRSF1ARARGRXRAPPARG | |
| SCHEMBL14045908 | 0.73 | TNFRSF1A (0.34) | TNFRSF1ARARGRXRAPPARG | |
| SCHEMBL459993 | 0.70 | MAOB (0.38) | — | |
| SCHEMBL458094 | 0.70 | — | — | |
| SCHEMBL460486 | 0.70 | CA1 (0.43) | TNFRSF1ACA1CA2 | |
| SCHEMBL458031 | 0.68 | KMT2A (0.48) | — | |
| SCHEMBL14615433 | 0.66 | RARG (0.33) | TNFRSF1ARARGRXRAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031358-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2012-03-15 | — | — | WO | disclosed |